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The next wave of tobacco harm reduction? Emerging transitions from smoking to safer nicotine products in South Korea, Ireland and Estonia

This Briefing Paper considers three countries showing emerging but different shifts away from cigarettes: one incomplete, one stalled, and one accelerating. What happens next in South Korea, Ireland and Estonia will aid understanding of how tobacco harm reduction can be supported - and what happens when it is stalled or obstructed.

Smoking among people facing problems with drug use

A companion publication to ‘Integrating tobacco harm reduction into drug treatment and harm reduction services’, this Briefing Paper reveals the scale and impact of tobacco-related morbidity and mortality among people who use drugs.

What is tobacco harm reduction? 2026 edition

Tobacco harm reduction aims to reduce the health risks faced by people who use high-risk tobacco products, especially cigarettes, by helping them switch to safer nicotine products rather than demanding complete abstinence. Nicotine itself is not the main cause of the severe diseases linked to smoking; the greatest danger comes from burning tobacco and inhaling …

What are heated tobacco products?

Appearing on the market in the mid-2010s, heated tobacco products include brands such as IQOS, glo and Ploom. This Briefing Paper provides an introduction to this safer nicotine product category and explores their tobacco harm reduction potential.

Estimated Numbers of People Using Vapour Products (E-cigarettes and Heat-not-Burn) Globally (Millions)

- No Fire, No Smoke: The Global State of Tobacco Harm Reduction

According to the market analyst company Euromonitor, in 2011 there were an estimated seven million people who “were regular dual or sole users of e-cigarettes and vapour products” around the world – for this estimate Euromonitor combines data on e-cigarettes and HNB. That figure rose to around 35 million in 2016 and is estimated to …

Nicotine and medical research – a background

Despite misconceptions about nicotine, due to its association with smoking, this Briefing Paper explains why researchers are increasingly interested in the therapeutic potential of nicotine with respect to Parkinson’s disease, Alzheimer’s disease and mental health.

Tobacco harm reduction and the FCTC: issues and challenges at COP11

From 17th – 22nd November 2025, COP11 is taking place in Geneva. This Briefing Paper explores the efficacy of the FCTC in reducing smoking, and considers the challenges posed by COP11 to consumer access to safer nicotine products and tobacco harm reduction progress.

The Global State of Tobacco Harm Reduction 2024: A Situation Report

This Briefing Paper summarises The Global State of Tobacco Harm Reduction 2024: A Situation Report, which uses the latest evidence and new data projections to report on the current global THR situation and its potential to rapidly reduce the burden of disease and mortality associated with risky tobacco use.

Dead ends - the tobacco industry's quest for a ‘safe’ combustible cigarette

Tobacco companies spent decades denying any link between smoking and disease, while also trying to develop a ‘safe’ cigarette. This Briefing Paper sets out to tell the story of this quest, looking at the roles played both by those within and outside of the tobacco industry.

Safer nicotine product taxation and optimal strategies for public health

This Briefing Paper examines the current global situation regarding the taxation of safer nicotine products and how this relates to product accessibility, before offering evidence-based policy recommendations for optimal taxation strategies in support of harm reduction goals and public health.

O Estado Global da Redução de Danos do Tabaco 2024: Um Relatório de Situação

O Estado Global da Redução de Danos do Tabaco 2024: Um Relatório de Situação é uma publicação de múltiplos componentes, agrupada em duas partes: Perspectivas globais e Percepções regionais e nacionais. O quanto os PNS estão substituindo e servindo como alternativa aos produtos de tabaco combustíveis e ao tabaco oral de alto risco. …

Глобальное состояние снижения вреда от табака – 2024: Ситуационный отчет

«Глобальное состояние снижения вреда от табака – 2024: Ситуационный отчет» — это многокомпонентная публикация, состоящая из двух частей: «Глобальные перспективы» и «Региональные и национальные аспекты». Тема, объединяющая эти части — это степень, на которую БНП заменяют и замещают сжигаемые и рискованные табачные продукты орального применения. …