Tobacco harm reduction is a potentially life-saving intervention for millions of people across the world. To those who currently use high-risk tobacco products, like cigarettes and some oral tobaccos, it offers the chance to switch to a range of safer nicotine products (SNP) that pose fewer risks to their health.

Most people know that tobacco use is harmful to health and that people use tobacco to consume nicotine. It is less well known that nicotine itself does not cause the severe illnesses associated with high-risk tobacco products like cigarettes. Nicotine is a comparatively low-risk drug, but its effects encourage repeated use. This is one of the reasons people find it hard to stop smoking, even when they know it is bad for their health.

The most dangerous way of using nicotine is by burning a cigarette and inhaling the smoke. Burning tobacco releases tar and gases containing thousands of toxins, many of which pose a risk of severe illness, leading to premature death in half of all smokers. Some oral tobacco products also release dangerous toxins when consumed.

In contrast, safer nicotine products are non-combustible: none of them burn tobacco and some of them do not contain any tobacco at all. They include nicotine vapes (e-cigarettes), nicotine pouchesSwedish-style snus (an oral tobacco), many US smokeless (chewing) tobaccos and heated tobacco products. Many of these products have only been developed in the last 10 – 15 years.