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Nicotine Replacement Therapy

Nicotine Gums

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Parts of the Model

  1. Forming Film Clear PVC film with a PVDC coating, heated and formed into a pocket for each piece. The coating slows moisture passing through, which keeps the gum from drying out or turning sticky.
  2. Lidding Foil Thin, hard aluminium foil heat-sealed to the film everywhere except over the pockets. It is brittle enough to tear when a piece is pushed through it.
  3. Gum Piece A coated piece of gum, usually with 2 mg or 4 mg of nicotine bound to an ion-exchange resin (nicotine polacrilex) and released as it is chewed. A buffer raises the pH of the saliva, so more nicotine is absorbed through the lining of the mouth.
  4. Coating The hard outer shell of each piece, built up from many thin layers of xylitol syrup in a rotating pan and polished with carnauba wax.
  5. Gum Centre The chewy inside of each piece: gum base mixed with the nicotine resin, buffer salts, sweeteners and flavourings, then rolled into a sheet and cut into pellets before coating.

Medicinal products designed to deliver nicotine without tobacco use, primarily to support smoking cessation and alleviate nicotine withdrawal symptoms.

This category includes nicotine patches, chewing gums, lozenges, inhalators, and oral or nasal nicotine sprays.

The defining characteristic is the therapeutic purpose of delivering nicotine as a substitute for nicotine previously obtained through tobacco use.

The arrival of innovative nicotine-containing products onto the market has constituted the most significant disruption to the global tobacco industry since the invention of the cigaretterolling machine.

  • Smoking Tobacco
  • Nicotine Vapes (E-cigarettes)
  • Snus
  • Heated Tobacco Products
  • Nicotine Replacement Therapy
  • Nicotine Pouches
  • Traditional Smokeless
Learn More

The primary source of the many health problems associated with the combustible cigarette lie in the act of inhaling the smoke released when it burns. Remove that risk and there is the possibility of nicotine consumption being relatively safe.

  • Smoking Tobacco
  • Nicotine Vapes (E-cigarettes)
  • Snus
  • Heated Tobacco Products
  • Nicotine Replacement Therapy
  • Nicotine Pouches
  • Traditional Smokeless
Learn More

Many people who were smoking have been motivated to switch to safer nicotine products, on the understanding that they can continue to consume nicotine but at much lower risk to their health.

  • Smoking Tobacco
  • Nicotine Vapes (E-cigarettes)
  • Snus
  • Heated Tobacco Products
  • Nicotine Replacement Therapy
  • Nicotine Pouches
  • Traditional Smokeless
Learn More
Oct
2025

Nicotine and Medical Research – A Background

Despite misconceptions about nicotine, due to its association with smoking, this Briefing Paper explains why researchers are increasingly interested in the therapeutic potential of nicotine with respect to Parkinson’s disease, Alzheimer’s disease and mental health.

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13 Languages
25056 Views
Mar
2025

Safer Nicotine Product Taxation and Optimal Strategies for Public Health

This Briefing Paper examines the current global situation regarding the taxation of safer nicotine products and how this relates to product accessibility, before offering evidence-based policy recommendations for optimal taxation strategies in support of harm reduction goals and public health.

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13 Languages
38909 Views